Location: A review of cardiac cellular electrophysiology models @ ae7a0b93f4ee / sed-ml / BR-INa-variants-standalone.xml

Author:
David Nickerson <david.nickerson@gmail.com>
Date:
2021-09-16 01:20:40+12:00
Desc:
Upadte jupyter notebook with MNT and DFN comparison figure
Permanent Source URI:
https://models.fieldml.org/workspace/a1/rawfile/ae7a0b93f4ee5fda3d81ba97eb459f958b2819c9/sed-ml/BR-INa-variants-standalone.xml

<?xml version="1.0" encoding="utf-8"?>

<sedML xmlns="http://www.biomodels.net/sed-ml" level="1" version="1">
  <listOfSimulations>
		<uniformTimeCourse id="simulation"
			initialTime="0"
			outputStartTime="0"
			outputEndTime="1500"
			numberOfPoints="1500">
      <algorithm kisaoID="KISAO:0000019" />
    </uniformTimeCourse>
		<!-- 
		FIXME: need to reference IVOI - can't go here though...
		-->
  </listOfSimulations>
  <listOfModels>
		<model id="BR"
			language="urn:sedml:language:cellml"
			source="http://models.cellml.org/workspace/a1/@@rawfile/7bc23d0526e23d54d45e1fb7deda0f55d7f0f086/models/1977_beeler/experiments/periodic-stimulus.xml" />
		<model id="BREJ"
			language="urn:sedml:language:cellml"
			source="http://models.cellml.org/workspace/a1/@@rawfile/7bc23d0526e23d54d45e1fb7deda0f55d7f0f086/models/1977_beeler/experiments/1980_ebihara_johnson.xml" />
		<model id="BRDR"
			language="urn:sedml:language:cellml"
			source="http://models.cellml.org/workspace/a1/@@rawfile/7bc23d0526e23d54d45e1fb7deda0f55d7f0f086/models/1977_beeler/experiments/1987_drouhard_roberge.xml" />
  </listOfModels>
  <listOfTasks>
    <task id="BRtask" modelReference="BR" simulationReference="simulation" />
    <task id="BREJtask" modelReference="BREJ" simulationReference="simulation" />
    <task id="BRDRtask" modelReference="BRDR" simulationReference="simulation" />
  </listOfTasks>
  <listOfDataGenerators>
    <dataGenerator id="BRtime" name="BR time">
      <listOfVariables>
        <variable id="BRtime_variable" taskReference="BRtask" target="/cellml:model/cellml:component[@name='time']/cellml:variable[@name='time']" />
      </listOfVariables>
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <ci> BRtime_variable </ci>
      </math>
    </dataGenerator>
    <dataGenerator id="BRVm" name="BR Vm">
      <listOfVariables>
        <variable id="BRVm_variable" taskReference="BRtask" target="/cellml:model/cellml:component[@name='exposed_variables']/cellml:variable[@name='Vm']" />
      </listOfVariables>
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <ci> BRVm_variable </ci>
      </math>
    </dataGenerator>
    <dataGenerator id="BREJtime" name="BREJ time">
      <listOfVariables>
        <variable id="BREJtime_variable" taskReference="BREJtask" target="/cellml:model/cellml:component[@name='time']/cellml:variable[@name='time']" />
      </listOfVariables>
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <ci> BREJtime_variable </ci>
      </math>
    </dataGenerator>
    <dataGenerator id="BREJVm" name="BREJ Vm">
      <listOfVariables>
        <variable id="BREJVm_variable" taskReference="BREJtask" target="/cellml:model/cellml:component[@name='fast_sodium_current']/cellml:variable[@name='V']" />
      </listOfVariables>
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <ci> BREJVm_variable </ci>
      </math>
    </dataGenerator>
    <dataGenerator id="BRDRtime" name="BRDR time">
      <listOfVariables>
        <variable id="BRDRtime_variable" taskReference="BRDRtask" target="/cellml:model/cellml:component[@name='time']/cellml:variable[@name='time']" />
      </listOfVariables>
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <ci> BRDRtime_variable </ci>
      </math>
    </dataGenerator>
    <dataGenerator id="BRDRVm" name="BRDR Vm">
      <listOfVariables>
        <variable id="BRDRVm_variable" taskReference="BRDRtask" target="/cellml:model/cellml:component[@name='fast_sodium_current']/cellml:variable[@name='V']" />
      </listOfVariables>
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <ci> BRDRVm_variable </ci>
      </math>
    </dataGenerator>
  </listOfDataGenerators>
  <listOfOutputs>
    <plot2D id="plot1" name="Action Potentials">
      <listOfCurves>
        <curve id="curve_0" logX="false" logY="false" xDataReference="BRtime" yDataReference="BRVm" />
        <curve id="curve_1" logX="false" logY="false" xDataReference="BREJtime" yDataReference="BREJVm" />
        <curve id="curve_2" logX="false" logY="false" xDataReference="BRDRtime" yDataReference="BRDRVm" />
      </listOfCurves>
    </plot2D>
  </listOfOutputs>
</sedML>