- Author:
- Leyla <lnor300>
- Date:
- 2022-09-28 16:08:33+13:00
- Desc:
- ..
- Permanent Source URI:
- https://models.fieldml.org/workspace/919/rawfile/3affededfd25a44594b79661e39fb68801515613/T_type_Ca/ICa_T.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="ICa_T" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="../Common/units.cellml">
<units name="current_units" units_ref="current_units"/>
<units name="voltage_units" units_ref="voltage_units"/>
<units name="time_units" units_ref="time_units"/>
<units name="conductance_units" units_ref="conductance_units"/>
<units name="millimolar" units_ref="millimolar"/>
<units name="Inverse_Voltage_units" units_ref="Inverse_Voltage_units"/>
</import>
<component name="d_LVA_SM">
<variable name="Vm_SM" public_interface="in" units="voltage_units"/>
<variable name="time" public_interface="in" units="time_units"/>
<variable name="d_inf_LVA_SM" units="dimensionless"/>
<variable name="tau_d_LVA_SM" units="time_units"/>
<variable initial_value="0.02" name="d_LVA_SM" public_interface="out" units="dimensionless"/>
<variable name="T_correction_Ca" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>d_inf_LVA_SM</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>Vm_SM</ci>
<cn cellml:units="voltage_units">27.5</cn>
</apply>
<apply>
<minus/>
<cn cellml:units="voltage_units">10.9</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_d_LVA_SM</ci>
<apply>
<times/>
<ci>T_correction_Ca</ci>
<cn cellml:units="time_units">3.0</cn>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>d_LVA_SM</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>d_inf_LVA_SM</ci>
<ci>d_LVA_SM</ci>
</apply>
<ci>tau_d_LVA_SM</ci>
</apply>
</apply>
</math>
</component>
<component name="f_LVA_SM">
<variable name="Vm_SM" public_interface="in" units="voltage_units"/>
<variable name="time" public_interface="in" units="time_units"/>
<variable name="f_inf_LVA_SM" units="dimensionless"/>
<variable name="tau_f_LVA_SM" units="time_units"/>
<variable initial_value="0.99" name="f_LVA_SM" public_interface="out" units="dimensionless"/>
<variable name="T_correction_Ca" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>f_inf_LVA_SM</ci>
<apply>
<divide/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<plus/>
<cn cellml:units="dimensionless">1.0</cn>
<apply>
<exp/>
<apply>
<divide/>
<apply>
<plus/>
<ci>Vm_SM</ci>
<cn cellml:units="voltage_units">15.8</cn>
</apply>
<cn cellml:units="voltage_units">7</cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>tau_f_LVA_SM</ci>
<apply>
<times/>
<ci>T_correction_Ca</ci>
<cn cellml:units="time_units">7.58</cn>
<apply>
<exp/>
<apply>
<times/>
<ci>Vm_SM</ci>
<cn cellml:units="Inverse_Voltage_units">0.00817</cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>time</ci>
</bvar>
<ci>f_LVA_SM</ci>
</apply>
<apply>
<divide/>
<apply>
<minus/>
<ci>f_inf_LVA_SM</ci>
<ci>f_LVA_SM</ci>
</apply>
<ci>tau_f_LVA_SM</ci>
</apply>
</apply>
</math>
</component>
<component name="I_LVA_SM">
<variable name="I_LVA_SM" private_interface="out" public_interface="out" units="current_units"/>
<variable name="Vm_SM" private_interface="out" public_interface="in" units="voltage_units"/>
<variable name="time" private_interface="out" public_interface="in" units="time_units"/>
<variable name="E_Ca" units="voltage_units"/>
<variable initial_value="0.18" name="G_max_LVA" units="conductance_units"/>
<variable name="f_LVA_SM" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="d_LVA_SM" private_interface="in" public_interface="out" units="dimensionless"/>
<variable name="RToF" public_interface="in" units="voltage_units"/>
<variable name="Ca_o" public_interface="in" units="millimolar"/>
<variable name="Ca_i" public_interface="in" units="millimolar"/>
<variable name="T_correction_Ca" private_interface="out" public_interface="in" units="dimensionless"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>E_Ca</ci>
<apply>
<times/>
<cn cellml:units="dimensionless">0.5</cn>
<ci>RToF</ci>
<apply>
<ln/>
<apply>
<divide/>
<ci>Ca_o</ci>
<ci>Ca_i</ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>I_LVA_SM</ci>
<apply>
<times/>
<ci>G_max_LVA</ci>
<ci>f_LVA_SM</ci>
<ci>d_LVA_SM</ci>
<apply>
<minus/>
<ci>Vm_SM</ci>
<ci>E_Ca</ci>
</apply>
</apply>
</apply>
</math>
</component>
<connection>
<map_components component_1="d_LVA_SM" component_2="I_LVA_SM"/>
<map_variables variable_1="Vm_SM" variable_2="Vm_SM"/>
<map_variables variable_1="d_LVA_SM" variable_2="d_LVA_SM"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="T_correction_Ca" variable_2="T_correction_Ca"/>
</connection>
<connection>
<map_components component_1="f_LVA_SM" component_2="I_LVA_SM"/>
<map_variables variable_1="Vm_SM" variable_2="Vm_SM"/>
<map_variables variable_1="f_LVA_SM" variable_2="f_LVA_SM"/>
<map_variables variable_1="time" variable_2="time"/>
<map_variables variable_1="T_correction_Ca" variable_2="T_correction_Ca"/>
</connection>
<group>
<relationship_ref relationship="encapsulation"/>
<component_ref component="I_LVA_SM">
<component_ref component="d_LVA_SM"/>
<component_ref component="f_LVA_SM"/>
</component_ref>
</group>
</model>
