Location: Hodgkin & Huxley (1952) model @ ab2962b87966 / BG / default_values_BG.cellml

Author:
WeiweiAi <wai484@aucklanduni.ac.nz>
Date:
2022-03-31 10:48:40+13:00
Desc:
Add open channel IV of HH models; Add simulation and plot python scripts
Permanent Source URI:
https://models.fieldml.org/workspace/64f/rawfile/ab2962b8796666ad9938a2577611c954f006b5fd/BG/default_values_BG.cellml

<?xml version='1.0' encoding='UTF-8'?>
<model name="default_values_BG" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="../cellLib/BG/units_BG.cellml">
        <units name="per_fmol" units_ref="per_fmol"/>
        <units name="fmol" units_ref="fmol"/>
        <units name="fmol_per_sec" units_ref="fmol_per_sec"/>
        <units name="fF" units_ref="fF"/>
        <units name="fS" units_ref="fS"/>
        <units name="fC" units_ref="fC"/>
    </import>
    <component name="model_para">
        <variable initial_value="279.45" name="T" public_interface="out" units="kelvin"/>
        <variable initial_value="3e+08" name="C_m" public_interface="out" units="fF"/>
        <variable initial_value="9e+10" name="g_leak" public_interface="out" units="fS"/>
        <variable initial_value="-54.387e-3" name="V_leak" public_interface="out" units="volt"/>
        <variable initial_value="0.0187525" name="K_i_Na" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.131206" name="K_e_Na" public_interface="out" units="per_fmol"/>
        <variable initial_value="333.869" name="K_S00" public_interface="out" units="per_fmol"/>
        <variable initial_value="2.87619" name="K_S10" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.0743331" name="K_S20" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.00576325" name="K_S30" public_interface="out" units="per_fmol"/>
        <variable initial_value="196098" name="K_S01" public_interface="out" units="per_fmol"/>
        <variable initial_value="1689.34" name="K_S11" public_interface="out" units="per_fmol"/>
        <variable initial_value="43.6597" name="K_S21" public_interface="out" units="per_fmol"/>
        <variable initial_value="3.38505" name="K_S31" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.00246044" name="kappa_Na" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="36.8464" name="kappa_m10" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="2851.42" name="kappa_m20" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="55165.4" name="kappa_m30" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.062733" name="kappa_m11" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="4.8547" name="kappa_m21" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="93.9222" name="kappa_m31" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.00635865" name="kappa_h0" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.738112" name="kappa_h1" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="28.56" name="kappa_h2" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="368.361" name="kappa_h3" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.84439" name="z_m_f" public_interface="out" units="dimensionless"/>
        <variable initial_value="-1.35836" name="z_m_r" public_interface="out" units="dimensionless"/>
        <variable initial_value="-1.23891" name="z_h_f" public_interface="out" units="dimensionless"/>
        <variable initial_value="1.03907" name="z_h_r" public_interface="out" units="dimensionless"/>
        <variable initial_value="1" name="z_Na" public_interface="out" units="dimensionless"/>
        <variable initial_value="0.05419" name="K_i_K" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.379151" name="K_e_K" public_interface="out" units="per_fmol"/>
        <variable initial_value="4160.94" name="K_S0" public_interface="out" units="per_fmol"/>
        <variable initial_value="80.5983" name="K_S1" public_interface="out" units="per_fmol"/>
        <variable initial_value="4.16322" name="K_S2" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.483855" name="K_S3" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.149958" name="K_S4" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.0205462" name="kappa_K" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.586755" name="kappa_n1" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="22.7187" name="kappa_n2" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="293.217" name="kappa_n3" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="1261.46" name="kappa_n4" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="0.744652" name="z_n_f" public_interface="out" units="dimensionless"/>
        <variable initial_value="-0.308314" name="z_n_r" public_interface="out" units="dimensionless"/>
        <variable initial_value="1" name="z_K" public_interface="out" units="dimensionless"/>
    </component>
    <component name="openCH_para">
        <variable initial_value="0.0795738" name="K_i_Na" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.556754" name="K_e_Na" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.044303" name="K_sa_Na" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.044303" name="kappa_Na" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="49.8173" name="q_sa_Na" public_interface="out" units="fmol"/>
        <variable initial_value="0.080643" name="K_i_K" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.564235" name="K_e_K" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.0455016" name="K_sa_K" public_interface="out" units="per_fmol"/>
        <variable initial_value="0.0455016" name="kappa_K" public_interface="out" units="fmol_per_sec"/>
        <variable initial_value="14.9452" name="q_sa_K" public_interface="out" units="fmol"/>
    </component>
    <component name="initials">
        <variable initial_value="-1.5e+07" name="q_m_init" public_interface="out" units="fmol"/>
        <variable initial_value="2.57296e+08" name="q_i_Na_init" public_interface="out" units="fmol"/>
        <variable initial_value="2.93304e+08" name="q_e_Na_init" public_interface="out" units="fmol"/>
        <variable initial_value="2.07556e+09" name="q_i_K_init" public_interface="out" units="fmol"/>
        <variable initial_value="1.212e+07" name="q_e_K_init" public_interface="out" units="fmol"/>
        <variable initial_value="20.7643" name="q_S00_init" public_interface="out" units="fmol"/>
        <variable initial_value="16.57" name="q_S01_init" public_interface="out" units="fmol"/>
        <variable initial_value="6.28813" name="q_S10_init" public_interface="out" units="fmol"/>
        <variable initial_value="5.01792" name="q_S11_init" public_interface="out" units="fmol"/>
        <variable initial_value="0.63475" name="q_S20_init" public_interface="out" units="fmol"/>
        <variable initial_value="0.506531" name="q_S21_init" public_interface="out" units="fmol"/>
        <variable initial_value="0.0213581" name="q_S30_init" public_interface="out" units="fmol"/>
        <variable initial_value="0.0170439" name="q_S31_init" public_interface="out" units="fmol"/>
        <variable initial_value="1.58967" name="q_S0_init" public_interface="out" units="fmol"/>
        <variable initial_value="4.77658" name="q_S1_init" public_interface="out" units="fmol"/>
        <variable initial_value="5.38219" name="q_S2_init" public_interface="out" units="fmol"/>
        <variable initial_value="2.69537" name="q_S3_init" public_interface="out" units="fmol"/>
        <variable initial_value="0.506185" name="q_S4_init" public_interface="out" units="fmol"/>
    </component>
</model>