Location: NVC @ 866c504b253f / coupling / Blood.cellml

Author:
Soroush Safaei <ssaf006@aucklanduni.ac.nz>
Date:
2019-03-06 21:20:11+13:00
Desc:
fixing the param
Permanent Source URI:
https://models.fieldml.org/workspace/4bd/rawfile/866c504b253f511a51609d674ff66944e702a8aa/coupling/Blood.cellml

<?xml version='1.0'?>
<!--parameter set p9-->
<model name="Blood_module" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="Units.cellml">
        <units name="mM" units_ref="mM"/>
        <units name="per_s" units_ref="per_s"/>
        <units name="mM_per_s" units_ref="mM_per_s"/>
        <units name="per_mM" units_ref="per_mM"/>
        <units name="per_mM_s" units_ref="per_mM_s"/>
        <units name="m3_per_s" units_ref="m3_per_s"/>
    </import>
    <component name="Blood">
        <variable name="t" public_interface="in" units="second"/>
        <variable name="q_inputDelay" public_interface="in" units="mM"/>
        <variable initial_value="5.5452" name="q_oHb" public_interface="out" units="mM"/>
        <variable initial_value="14.4548" name="q_dHb" public_interface="out" units="mM"/>
        <variable initial_value="0.7976" name="q_O_2" public_interface="out" units="mM"/>
        <variable initial_value="6.8492" name="q_glucose" public_interface="out" units="mM"/>
        <variable name="k_flow" public_interface="out" units="per_s"/>
        <variable initial_value="10" name="q_G_body" units="mM"/>
        <variable initial_value="10" name="q_O_2_body" units="mM"/>
        <variable initial_value="10" name="q_oHb_body" units="mM"/>
        <variable initial_value="10" name="q_dHb_body" units="mM"/>
        <variable name="v_basal" units="mM_per_s"/>
        <variable name="v_stim" units="mM_per_s"/>
        <variable name="q_HETE" public_interface="in" units="mM"/>
        <variable name="q_EET" public_interface="in" units="mM"/>
        <variable name="q_PG" public_interface="in" units="mM"/>
        <variable name="q_cGMP" public_interface="in" units="mM"/>
        <variable name="k_Stimulating" public_interface="out" units="per_s"/>
        <variable name="k_Inhibiting" public_interface="out" units="per_s"/>
        <variable name="k_Act" public_interface="out" units="per_s"/>
        <variable initial_value="198.8573" name="k_1_f" units="per_s"/>
        <variable initial_value="50.9727" name="k_1_b" units="per_mM_s"/>
        <variable initial_value="4.1354" name="k_basal" units="per_mM_s"/>
        <variable initial_value="2.2892" name="k_flow_basal" public_interface="out" units="per_s"/>
        <!--var k_flow_basal: m3_per_s {pub: in};-->
        <variable initial_value="10.5475" name="proportion_1" public_interface="out" units="dimensionless"/>
        <variable initial_value="3.6952" name="proportion_2" public_interface="out" units="dimensionless"/>
        <variable initial_value="19.7612" name="b_1" public_interface="out" units="per_mM_s"/>
        <variable initial_value="0.2549" name="b_2" public_interface="out" units="per_mM_s"/>
        <variable initial_value="14.2989" name="b_3" public_interface="out" units="per_mM_s"/>
        <variable initial_value="2.8037" name="b_4" public_interface="out" units="per_mM_s"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <ci>k_Stimulating</ci>
                <apply>
                    <plus/>
                    <apply>
                        <times/>
                        <ci>b_1</ci>
                        <ci>q_cGMP</ci>
                    </apply>
                    <apply>
                        <times/>
                        <ci>b_2</ci>
                        <ci>q_PG</ci>
                    </apply>
                    <apply>
                        <times/>
                        <ci>b_3</ci>
                        <ci>q_EET</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>k_Inhibiting</ci>
                <apply>
                    <times/>
                    <ci>b_4</ci>
                    <ci>q_HETE</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>k_Act</ci>
                <apply>
                    <minus/>
                    <ci>k_Stimulating</ci>
                    <ci>k_Inhibiting</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>k_flow</ci>
                <apply>
                    <plus/>
                    <ci>k_flow_basal</ci>
                    <ci>k_Act</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_basal</ci>
                <apply>
                    <times/>
                    <ci>k_basal</ci>
                    <apply>
                        <power/>
                        <ci>q_O_2</ci>
                        <ci>proportion_1</ci>
                    </apply>
                    <ci>q_glucose</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <ci>v_stim</ci>
                <apply>
                    <times/>
                    <ci>q_inputDelay</ci>
                    <apply>
                        <power/>
                        <ci>q_O_2</ci>
                        <ci>proportion_2</ci>
                    </apply>
                    <ci>q_glucose</ci>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_oHb</ci>
                </apply>
                <apply>
                    <minus/>
                    <apply>
                        <plus/>
                        <apply>
                            <minus/>
                            <apply>
                                <times/>
                                <ci>k_1_b</ci>
                                <ci>q_dHb</ci>
                                <ci>q_O_2</ci>
                            </apply>
                            <apply>
                                <times/>
                                <ci>k_1_f</ci>
                                <ci>q_oHb</ci>
                            </apply>
                        </apply>
                        <apply>
                            <times/>
                            <ci>q_oHb_body</ci>
                            <ci>k_flow</ci>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <ci>q_oHb</ci>
                        <ci>k_flow</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_dHb</ci>
                </apply>
                <apply>
                    <minus/>
                    <apply>
                        <plus/>
                        <apply>
                            <minus/>
                            <apply>
                                <times/>
                                <ci>k_1_f</ci>
                                <ci>q_oHb</ci>
                            </apply>
                            <apply>
                                <times/>
                                <ci>k_1_b</ci>
                                <ci>q_dHb</ci>
                                <ci>q_O_2</ci>
                            </apply>
                        </apply>
                        <apply>
                            <times/>
                            <ci>q_dHb_body</ci>
                            <ci>k_flow</ci>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <ci>q_dHb</ci>
                        <ci>k_flow</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_O_2</ci>
                </apply>
                <apply>
                    <minus/>
                    <apply>
                        <plus/>
                        <apply>
                            <minus/>
                            <apply>
                                <minus/>
                                <apply>
                                    <minus/>
                                    <apply>
                                        <times/>
                                        <ci>k_1_f</ci>
                                        <ci>q_oHb</ci>
                                    </apply>
                                    <apply>
                                        <times/>
                                        <ci>k_1_b</ci>
                                        <ci>q_dHb</ci>
                                        <ci>q_O_2</ci>
                                    </apply>
                                </apply>
                                <apply>
                                    <times/>
                                    <ci>v_basal</ci>
                                    <ci>proportion_1</ci>
                                </apply>
                            </apply>
                            <apply>
                                <times/>
                                <ci>v_stim</ci>
                                <ci>proportion_2</ci>
                            </apply>
                        </apply>
                        <apply>
                            <times/>
                            <ci>q_O_2_body</ci>
                            <ci>k_flow</ci>
                        </apply>
                    </apply>
                    <apply>
                        <times/>
                        <ci>q_O_2</ci>
                        <ci>k_flow</ci>
                    </apply>
                </apply>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>t</ci>
                    </bvar>
                    <ci>q_glucose</ci>
                </apply>
                <apply>
                    <minus/>
                    <apply>
                        <minus/>
                        <apply>
                            <minus/>
                            <apply>
                                <times/>
                                <ci>q_G_body</ci>
                                <ci>k_flow</ci>
                            </apply>
                            <apply>
                                <times/>
                                <ci>q_glucose</ci>
                                <ci>k_flow</ci>
                            </apply>
                        </apply>
                        <ci>v_basal</ci>
                    </apply>
                    <ci>v_stim</ci>
                </apply>
            </apply>
        </math>
    </component>
</model>