- Author:
- Soroush Safaei <ssaf006@aucklanduni.ac.nz>
- Date:
- 2019-03-06 21:20:11+13:00
- Desc:
- fixing the param
- Permanent Source URI:
- https://models.fieldml.org/workspace/4bd/rawfile/866c504b253f511a51609d674ff66944e702a8aa/coupling/Blood.cellml
<?xml version='1.0'?>
<!--parameter set p9-->
<model name="Blood_module" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="Units.cellml">
<units name="mM" units_ref="mM"/>
<units name="per_s" units_ref="per_s"/>
<units name="mM_per_s" units_ref="mM_per_s"/>
<units name="per_mM" units_ref="per_mM"/>
<units name="per_mM_s" units_ref="per_mM_s"/>
<units name="m3_per_s" units_ref="m3_per_s"/>
</import>
<component name="Blood">
<variable name="t" public_interface="in" units="second"/>
<variable name="q_inputDelay" public_interface="in" units="mM"/>
<variable initial_value="5.5452" name="q_oHb" public_interface="out" units="mM"/>
<variable initial_value="14.4548" name="q_dHb" public_interface="out" units="mM"/>
<variable initial_value="0.7976" name="q_O_2" public_interface="out" units="mM"/>
<variable initial_value="6.8492" name="q_glucose" public_interface="out" units="mM"/>
<variable name="k_flow" public_interface="out" units="per_s"/>
<variable initial_value="10" name="q_G_body" units="mM"/>
<variable initial_value="10" name="q_O_2_body" units="mM"/>
<variable initial_value="10" name="q_oHb_body" units="mM"/>
<variable initial_value="10" name="q_dHb_body" units="mM"/>
<variable name="v_basal" units="mM_per_s"/>
<variable name="v_stim" units="mM_per_s"/>
<variable name="q_HETE" public_interface="in" units="mM"/>
<variable name="q_EET" public_interface="in" units="mM"/>
<variable name="q_PG" public_interface="in" units="mM"/>
<variable name="q_cGMP" public_interface="in" units="mM"/>
<variable name="k_Stimulating" public_interface="out" units="per_s"/>
<variable name="k_Inhibiting" public_interface="out" units="per_s"/>
<variable name="k_Act" public_interface="out" units="per_s"/>
<variable initial_value="198.8573" name="k_1_f" units="per_s"/>
<variable initial_value="50.9727" name="k_1_b" units="per_mM_s"/>
<variable initial_value="4.1354" name="k_basal" units="per_mM_s"/>
<variable initial_value="2.2892" name="k_flow_basal" public_interface="out" units="per_s"/>
<!--var k_flow_basal: m3_per_s {pub: in};-->
<variable initial_value="10.5475" name="proportion_1" public_interface="out" units="dimensionless"/>
<variable initial_value="3.6952" name="proportion_2" public_interface="out" units="dimensionless"/>
<variable initial_value="19.7612" name="b_1" public_interface="out" units="per_mM_s"/>
<variable initial_value="0.2549" name="b_2" public_interface="out" units="per_mM_s"/>
<variable initial_value="14.2989" name="b_3" public_interface="out" units="per_mM_s"/>
<variable initial_value="2.8037" name="b_4" public_interface="out" units="per_mM_s"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>k_Stimulating</ci>
<apply>
<plus/>
<apply>
<times/>
<ci>b_1</ci>
<ci>q_cGMP</ci>
</apply>
<apply>
<times/>
<ci>b_2</ci>
<ci>q_PG</ci>
</apply>
<apply>
<times/>
<ci>b_3</ci>
<ci>q_EET</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<ci>k_Inhibiting</ci>
<apply>
<times/>
<ci>b_4</ci>
<ci>q_HETE</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k_Act</ci>
<apply>
<minus/>
<ci>k_Stimulating</ci>
<ci>k_Inhibiting</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>k_flow</ci>
<apply>
<plus/>
<ci>k_flow_basal</ci>
<ci>k_Act</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_basal</ci>
<apply>
<times/>
<ci>k_basal</ci>
<apply>
<power/>
<ci>q_O_2</ci>
<ci>proportion_1</ci>
</apply>
<ci>q_glucose</ci>
</apply>
</apply>
<apply>
<eq/>
<ci>v_stim</ci>
<apply>
<times/>
<ci>q_inputDelay</ci>
<apply>
<power/>
<ci>q_O_2</ci>
<ci>proportion_2</ci>
</apply>
<ci>q_glucose</ci>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_oHb</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<times/>
<ci>k_1_b</ci>
<ci>q_dHb</ci>
<ci>q_O_2</ci>
</apply>
<apply>
<times/>
<ci>k_1_f</ci>
<ci>q_oHb</ci>
</apply>
</apply>
<apply>
<times/>
<ci>q_oHb_body</ci>
<ci>k_flow</ci>
</apply>
</apply>
<apply>
<times/>
<ci>q_oHb</ci>
<ci>k_flow</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_dHb</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<times/>
<ci>k_1_f</ci>
<ci>q_oHb</ci>
</apply>
<apply>
<times/>
<ci>k_1_b</ci>
<ci>q_dHb</ci>
<ci>q_O_2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>q_dHb_body</ci>
<ci>k_flow</ci>
</apply>
</apply>
<apply>
<times/>
<ci>q_dHb</ci>
<ci>k_flow</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_O_2</ci>
</apply>
<apply>
<minus/>
<apply>
<plus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>k_1_f</ci>
<ci>q_oHb</ci>
</apply>
<apply>
<times/>
<ci>k_1_b</ci>
<ci>q_dHb</ci>
<ci>q_O_2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>v_basal</ci>
<ci>proportion_1</ci>
</apply>
</apply>
<apply>
<times/>
<ci>v_stim</ci>
<ci>proportion_2</ci>
</apply>
</apply>
<apply>
<times/>
<ci>q_O_2_body</ci>
<ci>k_flow</ci>
</apply>
</apply>
<apply>
<times/>
<ci>q_O_2</ci>
<ci>k_flow</ci>
</apply>
</apply>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>q_glucose</ci>
</apply>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<minus/>
<apply>
<times/>
<ci>q_G_body</ci>
<ci>k_flow</ci>
</apply>
<apply>
<times/>
<ci>q_glucose</ci>
<ci>k_flow</ci>
</apply>
</apply>
<ci>v_basal</ci>
</apply>
<ci>v_stim</ci>
</apply>
</apply>
</math>
</component>
</model>