- Author:
- Kenneth Tran <k.tran@auckland.ac.nz>
- Date:
- 2017-08-31 15:35:06+12:00
- Desc:
- Adding online links.
- Permanent Source URI:
- https://models.fieldml.org/workspace/4a2/rawfile/70c85f9bc526e95d066e088954387d87b82f72c9/README.rst
Computational code to reproduce simulation figures in the J. Physiol publication: "Experimental and modelling evidence of shortening heat in cardiac muscle."
DOI: `10.1113/JP274680 <https://dx.doi.org/10.1113/JP274680>`_
.. figure:: tran_2009.png
:scale: 80 %
:alt: Schematic of cross-bridge model.
Schematic of cross-bridge model.
Main.m
------
This script sets up and executes the model simulations in the presence of passive force. Run this code to simulate Figures 3, 4, 7 and 8.
PlotFigures.m
-------------
After Main.m has been executed, run this script to plot Figures 3, 4, 7 and 8.
Main_noPassive.m
----------------
This script sets up and executes the model simulations in the absence of passive force. Run this code to simulate Figures 6 and 7.
PlotFigures_noPassive.m
-----------------------
After Main_noPassive.m has been executed, run this script to plot Figures 6 and 7.
XBSolve.m
---------
A function that contains the algoritms for setting up isometric and work-loop contractions. This function is called by Main.m and Main_noPassive.m.
XBModel.m
---------
This function returns the RHS vector of the `Tran et al., (2010) model of cross-bridge cycling <https://models.physiomeproject.org/workspace/tran_2009>`_.
getDeriv.m
----------
This function calls XBModel.m to setup the RHS vector. It is also called after completion of a solve to return the Force and ATPase information.
getCai.m
--------
This function returns a Ca transient.
passiveForces.m
---------------
This function returns the passive force.
IC_XBModel.m
------------
This script file contains the initial parameters of the cross-bridge model.
Parameters_XBModel.m
--------------------
This script contains the parameters for the cross-bridge model.
Fevents.m
---------
This function is used to detect when the isotonic phase of the work-loop starts. It is used in the work-loop section of XBSolve.m when the ode15s solver is called. The Fevents function is setup using the 'options' argument of the solver on line 36.
