Location: Anion Exchanger @ f7d6864ac4cf / Weinstein_2000_AE1_Fig3C.cellml

Author:
Soroush Safaei <ssaf006@aucklanduni.ac.nz>
Date:
2017-01-23 18:50:16+13:00
Desc:
add SVG diagram
Permanent Source URI:
https://models.fieldml.org/workspace/290/rawfile/f7d6864ac4cfc1a517ec5385b6ab4d6a582a8d29/Weinstein_2000_AE1_Fig3C.cellml

<?xml version='1.0'?>
<model cmeta:id="Weinstein_2000_AE1" name="Weinstein_2000_AE1" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink">
    <import xlink:href="Units/Units.cellml">
        <units name="mM" units_ref="mM"/>
        <units name="mM_per_s" units_ref="mM_per_s"/>
        <units name="umol_per_s_per_cm2" units_ref="umol_per_s_per_cm2"/>
    </import>
    <import xlink:href="Weinstein_2000_AE1.cellml">
        <component component_ref="AE1" name="AE1"/>
    </import>
    <component name="environment">
        <variable name="time" public_interface="out" units="second"/>
    </component>
    <component name="concentrations">
        <variable name="time" public_interface="in" units="second"/>
        <variable initial_value="26.0" name="HCO3_int" public_interface="out" units="mM"/>
        <variable initial_value="1.0" name="HCO3_ext" public_interface="out" units="mM"/>
        <variable initial_value="29.0" name="Cl_int" public_interface="out" units="mM"/>
        <variable initial_value="114.0" name="Cl_ext" public_interface="out" units="mM"/>
        <math xmlns="http://www.w3.org/1998/Math/MathML">
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>HCO3_int</ci>
                </apply>
                <cn cellml:units="mM_per_s">0.0</cn>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>HCO3_ext</ci>
                </apply>
                <cn cellml:units="mM_per_s">1.0</cn>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>Cl_int</ci>
                </apply>
                <cn cellml:units="mM_per_s">0.0</cn>
            </apply>
            <apply>
                <eq/>
                <apply>
                    <diff/>
                    <bvar>
                        <ci>time</ci>
                    </bvar>
                    <ci>Cl_ext</ci>
                </apply>
                <cn cellml:units="mM_per_s">0.0</cn>
            </apply>
        </math>
    </component>
    <component name="fluxes">
        <variable name="J_AE1_HCO3" public_interface="in" units="umol_per_s_per_cm2"/>
        <variable name="J_AE1_Cl" public_interface="in" units="umol_per_s_per_cm2"/>
    </component>
    <connection>
        <map_components component_1="concentrations" component_2="AE1"/>
        <map_variables variable_1="HCO3_int" variable_2="HCO3_int"/>
        <map_variables variable_1="HCO3_ext" variable_2="HCO3_ext"/>
        <map_variables variable_1="Cl_int" variable_2="Cl_int"/>
        <map_variables variable_1="Cl_ext" variable_2="Cl_ext"/>
    </connection>
    <connection>
        <map_components component_1="fluxes" component_2="AE1"/>
        <map_variables variable_1="J_AE1_HCO3" variable_2="J_AE1_HCO3"/>
        <map_variables variable_1="J_AE1_Cl" variable_2="J_AE1_Cl"/>
    </connection>
    <connection>
        <map_components component_1="concentrations" component_2="environment"/>
        <map_variables variable_1="time" variable_2="time"/>
    </connection>
    <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
        <!--
      The following RDF block contains metadata that applies to this document
      as a whole, as indicated by the empty about attribute on the 
      <rdf:Description> element.
    -->
        <rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="">
            <!--
        The Model Builder Metadata.  The Dublin Core "creator" element is used  
        to indicate the person who translated the model into CellML.
      -->
            <dc:creator xmlns:dc="http://purl.org/dc/elements/1.1/" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                <vCard:N xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                    <vCard:Family xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">Terkildsen</vCard:Family>
                    <vCard:Given xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">Jonna</vCard:Given>
                </vCard:N>
                <vCard:EMAIL xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                    <rdf:value xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">j.terkildsen@auckland.ac.nz</rdf:value>
                    <rdf:type xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:resource="http://imc.org/vCard/3.0#internet"/>
                </vCard:EMAIL>
                <vCard:ORG xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                    <vCard:Orgname xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">Auckland Bioengineering Institute</vCard:Orgname>
                </vCard:ORG>
            </dc:creator>
            <!--
        The Creation Date metadata. This is the date on which the model
        was translated into CellML.
      -->
            <dcterms:created xmlns:dcterms="http://purl.org/dc/terms/" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                <dcterms:W3CDTF xmlns:dcterms="http://purl.org/dc/terms/">2009-11-11</dcterms:W3CDTF>
            </dcterms:created>
            <!--
        The Modification History metadata. This lists the changes that have been
        made to the document, who made the changes, and when they were made.
      -->
        </rdf:Description>
        <!--
      The following metadata refers to the model itself, as indicated by the
      reference to the ID "weinstein_2000_AE1", which is    
      declared on the <model> element.
    -->
        <rdf:Description xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:about="#weinstein_2000_AE1">
            <!-- A human readable name for the model. -->
            <dc:title xmlns:dc="http://purl.org/dc/elements/1.1/">&#xd;
        The Weinstein 2000 quantitative model of AE1 (Cl/HCO3 exchanger).&#xd;
      </dc:title>
            <!-- A comment regarding the model. -->
            <cmeta:comment xmlns:cmeta="http://www.cellml.org/metadata/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                <rdf:value xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">&#xd;
          This is the CellML description of the Weinstein 2000 quantitative model of AE1 (Cl/HCO3 exchanger)&#xd;
        </rdf:value>
                <!-- The creator of the comment. -->
                <dc:creator xmlns:dc="http://purl.org/dc/elements/1.1/" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                    <vCard:FN xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">Jonna Terkildsen</vCard:FN>
                </dc:creator>
            </cmeta:comment>
            <!--  Keyword(s) -->
            <bqs:reference xmlns:bqs="http://www.cellml.org/bqs/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                <dc:subject xmlns:dc="http://purl.org/dc/elements/1.1/" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                    <bqs:subject_type xmlns:bqs="http://www.cellml.org/bqs/1.0#">keyword</bqs:subject_type>
                    <rdf:value xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                        <rdf:Bag xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                            <rdf:li xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">renal</rdf:li>
                            <rdf:li xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">ion transport</rdf:li>
                            <rdf:li xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">kidney</rdf:li>
                            <rdf:li xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">medullary collecting duct</rdf:li>
                        </rdf:Bag>
                    </rdf:value>
                </dc:subject>
            </bqs:reference>
            <bqs:reference xmlns:bqs="http://www.cellml.org/bqs/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                <bqs:Pubmed_id xmlns:bqs="http://www.cellml.org/bqs/1.0#">10894785</bqs:Pubmed_id>
                <bqs:JournalArticle xmlns:bqs="http://www.cellml.org/bqs/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                    <dc:creator xmlns:dc="http://purl.org/dc/elements/1.1/">
                        <rdf:Seq xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                            <rdf:li xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:parseType="Resource">
                                <bqs:Person xmlns:bqs="http://www.cellml.org/bqs/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                                    <vCard:N xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                                        <vCard:Family xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">Weinstein</vCard:Family>
                                        <vCard:Given xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">A</vCard:Given>
                                        <vCard:Other xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#">M</vCard:Other>
                                    </vCard:N>
                                </bqs:Person>
                            </rdf:li>
                        </rdf:Seq>
                    </dc:creator>
                    <dc:title xmlns:dc="http://purl.org/dc/elements/1.1/">&#xd;
           A mathematical model of the outer medullary collecting duct of the rat&#xd;
          </dc:title>
                    <dcterms:issued xmlns:dcterms="http://purl.org/dc/terms/" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                        <dcterms:W3CDTF xmlns:dcterms="http://purl.org/dc/terms/">2000-07</dcterms:W3CDTF>
                    </dcterms:issued>
                    <bqs:Journal xmlns:bqs="http://www.cellml.org/bqs/1.0#" rdf:parseType="Resource" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
                        <dc:title xmlns:dc="http://purl.org/dc/elements/1.1/">American Journal of Physiology</dc:title>
                    </bqs:Journal>
                    <bqs:volume xmlns:bqs="http://www.cellml.org/bqs/1.0#">279</bqs:volume>
                    <bqs:first_page xmlns:bqs="http://www.cellml.org/bqs/1.0#">24</bqs:first_page>
                    <bqs:last_page xmlns:bqs="http://www.cellml.org/bqs/1.0#">45</bqs:last_page>
                </bqs:JournalArticle>
            </bqs:reference>
        </rdf:Description>
    </rdf:RDF>
</model>