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Hunter, McCulloch, ter Keurs, 1998
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Modelling the mechanical properties of cardiac muscle
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Model Mathematics
Component based math viewer is available
Component: environment
Component: calcium_transient
d
d
time
Ca_i
=
Ca_o
+
Ca_max
-
Ca_o
time
tau_Ca
ⅇ
1.0
-
time
tau_Ca
Component: TnC_Ca_binding_kinetics
d
d
time
Ca_b
=
rho_0
Ca_i
Ca_b_max
-
Ca_b
-
rho_1
Ca_b
1.0
-
T
lambda
To
Component: thin_filament_kinetics
d
d
time
z
=
alpha_0
Ca_b
C_50
n
1.0
-
z
-
z
To
=
T_ref
1.0
+
beta_0
lambda
-
1.0
z
n
=
n_ref
1.0
+
beta_1
lambda
-
1.0
pC_50
=
pC_50_ref
1.0
+
beta_2
lambda
-
1.0
Component: crossbridge_kinetics
dlambda_dt
=
alpha_1
A1
T
To
-
1.0
T
To
+
a
T
=
To
1.0
+
a
Q
1.0
-
Q
Q
=
A1
ⅇ
-
alpha_1
time
-
tau
dlambda_dt
tau
+
A2
ⅇ
-
alpha_2
time
-
tau
dlambda_dt
tau
+
A3
ⅇ
-
alpha_3
time
-
tau
dlambda_dt
tau
Source
Derived from workspace
Hunter, Mcculloch, Terkeurs, 1998
at changeset
fe533168688e
.
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Creative Commons Attribution 3.0 Unported License
.
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Modelling the mechanical properties of cardiac muscle