Location: Potassium delayed rectifier channel knowledge page @ 439cc27bace6 / exposure / exposure_frontpage.rst

Author:
Shelley Fong <sfon036@UoA.auckland.ac.nz>
Date:
2024-07-02 11:23:54+12:00
Desc:
Updating table
Permanent Source URI:
https://models.fieldml.org/workspace/b80/rawfile/439cc27bace6239ff514a38e7244cb91bb40dfda/exposure/exposure_frontpage.rst

About
====================

Landing page for the rapid delayed rectifier potassium channel (**Kr**).
Other names for this protein **Kv**, **Name2**

Kr is thought to be KCNE1 and/or KCNE2 assembled with KCNH2/HERG proteins.

Subfamilies
===================
KCNA (Kv1.x), KCNB (Kv2.x), ...

Pictures
===================
Insert 

Literature
===================

.. csv-table:: list (for further reading)
   :header: "Title", "Year"
   :widths: 30, 15   
   
   "Name 1", "2010"


Existing models 
===================

.. csv-table:: Link to other PMR workspaces or exposures
   :header: "Title", "Author"
   :widths: 30, 15
   
   "`BG_Kr <https://models.physiomeproject.org/workspace/82c>`_", "S Fong" 
   "`Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death*^ <https://models.physiomeproject.org/e/514>`_", "C Clancy and Y Rudy"
   "`Bond graph modelling of the cardiac action potential: Implications for drift and non-unique steady states^ <https://github.com/uomsystemsbiology/bond_graph_cardiac_AP>`_", "M Pan et al."
   
Models denoted by [*] are not in bond graph form.
Models denoted by [^] are part of a whole cell model.

Annotations
===================

.. csv-table:: 
   :header: "Item", "Database"
   :widths: 30, 15
   
   "KCNE1 structure", "`PDB <https://www.rcsb.org/structure/2K21>`_"
   "KCNE2 structure", "`Alphafold <https://alphafold.ebi.ac.uk/entry/Q9Y6J6>`_"
   "KCNE1 protein", "`Uniprot 1 <https://www.uniprot.org/uniprotkb/P15382/entry>`_"
   "KCNE2 protein", "`Uniprot 2 <https://www.uniprot.org/uniprotkb/Q9Y6J6/entry>`_"
   "Gene sequence", "Gene ontology AmiGO LINK"
   "Hierarchy of Kv channels", "`Interpro <https://www.ebi.ac.uk/interpro/entry/InterPro/IPR003968/>`_"