Location: VPH-MIP case study on CellML @ 6b9447fa179e / experiments / gNa-200.xml

Author:

David Nickerson <nickerso@users.sourceforge.net>

Date:

2012-09-26 15:32:59+12:00

Desc:

adding more information to the main documentation page for the workspace, including some useful direct links to various documents.

Permanent Source URI:

https://models.fieldml.org/w/andre/VPH-MIP/rawfile/6b9447fa179ec6c4ec0418f82b985750ce7fc2b7/experiments/gNa-200.xml

<?xml version="1.0" encoding="iso-8859-1"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" name="gNa_200" cmeta:id="gNa_200">
  

  <import xlink:href="../components/units.xml">
    <units name="ms" units_ref="ms"/>
    <units name="uA_per_cmsq" units_ref="uA_per_cmsq"/>
    <units name="mS_per_cmsq" units_ref="mS_per_cmsq"/>
  </import>
  <import xlink:href="../components/stimulated.xml">
    <component name="model" component_ref="action_potential"/>
  </import>
  <import xlink:href="periodic-IStim-protocol.xml">
    <component name="stimulus_protocol" component_ref="stimulus_protocol"/>
  </import>
  <import xlink:href="../components/default-variable-values.xml">
    <component name="default_parameters" component_ref="parameters"/>
    <component name="default_initial_conditions" component_ref="initial_conditions"/>
  </import>
  
  <component name="time" cmeta:id="time_component">
    
    <variable cmeta:id="time" name="time" initial_value="0.0" public_interface="out" units="ms"/>
  </component>
  <connection>
    <map_components component_1="model" component_2="time"/>
    <map_variables variable_1="time" variable_2="time"/>
  </connection>
  <connection>
    <map_components component_1="time" component_2="stimulus_protocol"/>
    <map_variables variable_1="time" variable_2="time"/>
  </connection>

  <component name="stimulus_protocol_params" cmeta:id="stimulus_protocol_params">
    
    <variable name="stimPeriod" initial_value="100" public_interface="out" units="ms"/>
    <variable name="stimDuration" initial_value="0.5" public_interface="out" units="ms"/>
    <variable name="stimCurrent" initial_value="-10.0" public_interface="out" units="uA_per_cmsq"/>
  </component>
  <connection>
    <map_components component_1="stimulus_protocol_params" component_2="stimulus_protocol"/>
    <map_variables variable_1="stimPeriod" variable_2="stimPeriod"/>
    <map_variables variable_1="stimDuration" variable_2="stimDuration"/>
    <map_variables variable_1="stimCurrent" variable_2="stimCurrent"/>
  </connection>
  <connection>
    <map_components component_1="model" component_2="stimulus_protocol"/>
    <map_variables variable_1="Istim" variable_2="IStim"/>
  </connection>

  <component name="parameters" cmeta:id="parameters">
    
    <variable cmeta:id="gNa_max" name="gNa_max" units="mS_per_cmsq" public_interface="out"/>
    <variable cmeta:id="gNa_max_control" name="gNa_max_control" units="mS_per_cmsq" public_interface="in"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML">
      <apply id="gNa_max_calculation"><eq/>
        <ci>gNa_max</ci>
        <apply><times/>
          <ci>gNa_max_control</ci>
          <cn cellml:units="dimensionless">2.0</cn>
        </apply>
      </apply>
    </math>
  </component>
  <connection>
    <map_components component_1="model" component_2="parameters"/>
    <map_variables variable_1="gNa_max" variable_2="gNa_max"/>
  </connection>
  <connection>
    <map_components component_1="parameters" component_2="default_parameters"/>
    <map_variables variable_1="gNa_max_control" variable_2="gNa_max"/>
  </connection>
  <connection>
    <map_components component_1="model" component_2="default_parameters"/>
    <map_variables variable_1="Cm" variable_2="Cm"/>
    <map_variables variable_1="VNa" variable_2="VNa"/>
    <map_variables variable_1="VK" variable_2="VK"/>
    <map_variables variable_1="Vleak" variable_2="Vleak"/>
    <map_variables variable_1="gK_max" variable_2="gK_max"/>
    <map_variables variable_1="gleak_max" variable_2="gleak_max"/>
    <map_variables variable_1="Tref_rates" variable_2="Tref_rates"/>
    <map_variables variable_1="T" variable_2="T"/>
    <map_variables variable_1="Q10_rates" variable_2="Q10_rates"/>
  </connection>
  
  <component name="initial_conditions" cmeta:id="initial_conditions">
    
  </component>
  <connection>
    <map_components component_1="model" component_2="default_initial_conditions"/>
    <map_variables variable_1="V_initial" variable_2="V_initial"/>
    <map_variables variable_1="m_initial" variable_2="m_initial"/>
    <map_variables variable_1="h_initial" variable_2="h_initial"/>
    <map_variables variable_1="n_initial" variable_2="n_initial"/>
  </connection>

</model>