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/* There are a total of 23 entries in the algebraic variable array. There are a total of 13 entries in each of the rate and state variable arrays. There are a total of 28 entries in the constant variable array. */ /* * VOI is time in component environment (minute). * STATES[0] is S1 in component S1 (millimolar). * ALGEBRAIC[13] is v8 in component v8 (flux). * ALGEBRAIC[15] is v9 in component v9 (flux). * CONSTANTS[0] is S in component S (millimolar). * ALGEBRAIC[0] is S2 in component S (millimolar). * STATES[1] is sul in component sul (millimolar). * ALGEBRAIC[5] is v1 in component v1 (flux). * ALGEBRAIC[6] is v2 in component v2 (flux). * STATES[2] is aps in component aps (millimolar). * ALGEBRAIC[7] is v3 in component v3 (flux). * STATES[3] is pap in component pap (millimolar). * ALGEBRAIC[8] is v4 in component v4 (flux). * STATES[4] is hyd in component hyd (millimolar). * ALGEBRAIC[9] is v5 in component v5 (flux). * ALGEBRAIC[11] is v17 in component v17 (flux). * STATES[5] is cys in component cys (millimolar). * ALGEBRAIC[12] is v6 in component v6 (flux). * STATES[6] is eth in component eth (millimolar). * CONSTANTS[1] is v13 in component v13 (flux). * ALGEBRAIC[10] is v7 in component v7 (flux). * STATES[7] is aco in component aco (millimolar). * ALGEBRAIC[14] is v15 in component v15 (flux). * STATES[8] is oxy in component oxy (millimolar). * CONSTANTS[2] is v10 in component v10 (flux). * ALGEBRAIC[18] is v11A in component v11A (flux). * ALGEBRAIC[19] is v14 in component v14 (flux). * STATES[9] is A3_c in component A3_c (millimolar). * ALGEBRAIC[21] is v12 in component v12 (flux). * ALGEBRAIC[22] is v16 in component v16 (flux). * STATES[10] is A3_m in component A3_m (millimolar). * ALGEBRAIC[20] is v11B in component v11B (flux). * CONSTANTS[3] is A_c in component A_c (millimolar). * ALGEBRAIC[1] is A2_c in component A_c (millimolar). * CONSTANTS[4] is A_m in component A_m (millimolar). * ALGEBRAIC[2] is A2_m in component A_m (millimolar). * STATES[11] is N2 in component N2 (millimolar). * CONSTANTS[5] is N in component N (millimolar). * ALGEBRAIC[3] is N1 in component N (millimolar). * STATES[12] is oah in component oah (millimolar). * ALGEBRAIC[17] is v18 in component v18 (flux). * CONSTANTS[6] is v0 in component v1 (flux). * ALGEBRAIC[4] is f1 in component v1 (dimensionless). * CONSTANTS[7] is n in component v1 (dimensionless). * CONSTANTS[8] is Kc in component v1 (millimolar). * CONSTANTS[9] is k2 in component v2 (second_order_rate_constant). * CONSTANTS[10] is k3 in component v3 (second_order_rate_constant). * CONSTANTS[11] is k4 in component v4 (second_order_rate_constant). * CONSTANTS[12] is k5 in component v5 (second_order_rate_constant). * CONSTANTS[13] is k6 in component v6 (first_order_rate_constant). * CONSTANTS[14] is k7 in component v7 (second_order_rate_constant). * CONSTANTS[15] is k8 in component v8 (second_order_rate_constant). * CONSTANTS[16] is k9 in component v9 (second_order_rate_constant). * CONSTANTS[17] is alpha in component v11A (dimensionless). * ALGEBRAIC[16] is f2 in component v11A (dimensionless). * CONSTANTS[18] is m in component v11A (dimensionless). * CONSTANTS[19] is KH in component v11A (millimolar). * CONSTANTS[20] is k11 in component v11A (first_order_rate_constant). * CONSTANTS[21] is KA in component v11B (millimolar). * CONSTANTS[22] is k12 in component v12 (first_order_rate_constant). * CONSTANTS[23] is k14 in component v14 (first_order_rate_constant). * CONSTANTS[24] is k15 in component v15 (first_order_rate_constant). * CONSTANTS[25] is k16 in component v16 (second_order_rate_constant). * CONSTANTS[26] is k17 in component v17 (first_order_rate_constant). * CONSTANTS[27] is k18 in component v18 (first_order_rate_constant). * RATES[0] is d/dt S1 in component S1 (millimolar). * RATES[1] is d/dt sul in component sul (millimolar). * RATES[2] is d/dt aps in component aps (millimolar). * RATES[3] is d/dt pap in component pap (millimolar). * RATES[4] is d/dt hyd in component hyd (millimolar). * RATES[5] is d/dt cys in component cys (millimolar). * RATES[6] is d/dt eth in component eth (millimolar). * RATES[7] is d/dt aco in component aco (millimolar). * RATES[8] is d/dt oxy in component oxy (millimolar). * RATES[9] is d/dt A3_c in component A3_c (millimolar). * RATES[10] is d/dt A3_m in component A3_m (millimolar). * RATES[11] is d/dt N2 in component N2 (millimolar). * RATES[12] is d/dt oah in component oah (millimolar). */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { STATES[0] = 1.892468811; CONSTANTS[0] = 2; STATES[1] = 0.012871557; STATES[2] = 0.053366179; STATES[3] = 0.082791522; STATES[4] = 0.159317029; STATES[5] = 0.805117739; STATES[6] = 10.25246999; CONSTANTS[1] = 4; STATES[7] = 1.139360412; STATES[8] = 6.146549084; CONSTANTS[2] = 80; STATES[9] = 1.570847601; STATES[10] = 1.835158493; CONSTANTS[3] = 2; CONSTANTS[4] = 2; STATES[11] = 1.933616149; CONSTANTS[5] = 2; STATES[12] = 5.571685096; CONSTANTS[6] = 1.6; CONSTANTS[7] = 4; CONSTANTS[8] = 0.1; CONSTANTS[9] = 0.2; CONSTANTS[10] = 0.2; CONSTANTS[11] = 0.2; CONSTANTS[12] = 0.1; CONSTANTS[13] = 0.12; CONSTANTS[14] = 10; CONSTANTS[15] = 10; CONSTANTS[16] = 10; CONSTANTS[17] = 0.1; CONSTANTS[18] = 4; CONSTANTS[19] = 0.5; CONSTANTS[20] = 10; CONSTANTS[21] = 1; CONSTANTS[22] = 5; CONSTANTS[23] = 10; CONSTANTS[24] = 5; CONSTANTS[25] = 10; CONSTANTS[26] = 0.02; CONSTANTS[27] = 1; } void computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[4] = pow(1.00000+pow(STATES[5]/CONSTANTS[8], CONSTANTS[7]), - 1.00000); ALGEBRAIC[5] = CONSTANTS[6]*ALGEBRAIC[4]; ALGEBRAIC[6] = CONSTANTS[9]*STATES[1]*STATES[9]; RATES[1] = ALGEBRAIC[5] - ALGEBRAIC[6]; ALGEBRAIC[7] = CONSTANTS[10]*STATES[2]*STATES[9]; RATES[2] = ALGEBRAIC[6] - ALGEBRAIC[7]; ALGEBRAIC[8] = CONSTANTS[11]*STATES[3]*STATES[11]; RATES[3] = ALGEBRAIC[7] - ALGEBRAIC[8]; ALGEBRAIC[9] = CONSTANTS[12]*STATES[4]*STATES[12]; ALGEBRAIC[11] = CONSTANTS[26]*STATES[4]; RATES[4] = ALGEBRAIC[8] - (ALGEBRAIC[9]+ALGEBRAIC[11]); ALGEBRAIC[12] = CONSTANTS[13]*STATES[5]; RATES[5] = ALGEBRAIC[9] - ALGEBRAIC[12]; ALGEBRAIC[3] = CONSTANTS[5] - STATES[11]; ALGEBRAIC[10] = CONSTANTS[14]*STATES[6]*ALGEBRAIC[3]; RATES[6] = CONSTANTS[1] - ALGEBRAIC[10]; ALGEBRAIC[0] = CONSTANTS[0] - STATES[0]; ALGEBRAIC[13] = CONSTANTS[15]*STATES[7]*ALGEBRAIC[0]; ALGEBRAIC[15] = CONSTANTS[16]*STATES[0]*ALGEBRAIC[3]; RATES[0] = ALGEBRAIC[13] - ALGEBRAIC[15]; ALGEBRAIC[14] = CONSTANTS[24]*STATES[7]; RATES[7] = ALGEBRAIC[10] - (ALGEBRAIC[13]+ALGEBRAIC[14]); ALGEBRAIC[17] = CONSTANTS[27]*STATES[12]; RATES[12] = ALGEBRAIC[14] - (ALGEBRAIC[9]+ALGEBRAIC[17]); ALGEBRAIC[16] = pow(1.00000+pow(STATES[4]/CONSTANTS[19], CONSTANTS[18]), - 1.00000); ALGEBRAIC[18] = ( CONSTANTS[20]*STATES[11]*STATES[8]*ALGEBRAIC[16])/( CONSTANTS[17]*STATES[11]+STATES[8]); RATES[11] = ( 2.00000*ALGEBRAIC[10]+ 4.00000*ALGEBRAIC[15]) - ( 3.00000*ALGEBRAIC[8]+ALGEBRAIC[18]); ALGEBRAIC[19] = CONSTANTS[23]*STATES[8]; RATES[8] = CONSTANTS[2] - (ALGEBRAIC[18]+ALGEBRAIC[19]); ALGEBRAIC[21] = CONSTANTS[22]*STATES[9]; ALGEBRAIC[1] = CONSTANTS[3] - STATES[9]; ALGEBRAIC[22] = CONSTANTS[25]*STATES[10]*ALGEBRAIC[1]; RATES[9] = ALGEBRAIC[22] - (ALGEBRAIC[6]+ALGEBRAIC[7]+ALGEBRAIC[21]); ALGEBRAIC[2] = CONSTANTS[4] - STATES[10]; ALGEBRAIC[20] = ( 3.00000*ALGEBRAIC[18]*ALGEBRAIC[2])/(CONSTANTS[21]+ALGEBRAIC[2]); RATES[10] = ALGEBRAIC[20] - ALGEBRAIC[22]; } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[4] = pow(1.00000+pow(STATES[5]/CONSTANTS[8], CONSTANTS[7]), - 1.00000); ALGEBRAIC[5] = CONSTANTS[6]*ALGEBRAIC[4]; ALGEBRAIC[6] = CONSTANTS[9]*STATES[1]*STATES[9]; ALGEBRAIC[7] = CONSTANTS[10]*STATES[2]*STATES[9]; ALGEBRAIC[8] = CONSTANTS[11]*STATES[3]*STATES[11]; ALGEBRAIC[9] = CONSTANTS[12]*STATES[4]*STATES[12]; ALGEBRAIC[11] = CONSTANTS[26]*STATES[4]; ALGEBRAIC[12] = CONSTANTS[13]*STATES[5]; ALGEBRAIC[3] = CONSTANTS[5] - STATES[11]; ALGEBRAIC[10] = CONSTANTS[14]*STATES[6]*ALGEBRAIC[3]; ALGEBRAIC[0] = CONSTANTS[0] - STATES[0]; ALGEBRAIC[13] = CONSTANTS[15]*STATES[7]*ALGEBRAIC[0]; ALGEBRAIC[15] = CONSTANTS[16]*STATES[0]*ALGEBRAIC[3]; ALGEBRAIC[14] = CONSTANTS[24]*STATES[7]; ALGEBRAIC[17] = CONSTANTS[27]*STATES[12]; ALGEBRAIC[16] = pow(1.00000+pow(STATES[4]/CONSTANTS[19], CONSTANTS[18]), - 1.00000); ALGEBRAIC[18] = ( CONSTANTS[20]*STATES[11]*STATES[8]*ALGEBRAIC[16])/( CONSTANTS[17]*STATES[11]+STATES[8]); ALGEBRAIC[19] = CONSTANTS[23]*STATES[8]; ALGEBRAIC[21] = CONSTANTS[22]*STATES[9]; ALGEBRAIC[1] = CONSTANTS[3] - STATES[9]; ALGEBRAIC[22] = CONSTANTS[25]*STATES[10]*ALGEBRAIC[1]; ALGEBRAIC[2] = CONSTANTS[4] - STATES[10]; ALGEBRAIC[20] = ( 3.00000*ALGEBRAIC[18]*ALGEBRAIC[2])/(CONSTANTS[21]+ALGEBRAIC[2]); }