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/* There are a total of 19 entries in the algebraic variable array. There are a total of 7 entries in each of the rate and state variable arrays. There are a total of 17 entries in the constant variable array. */ /* * VOI is time in component environment (second). * CONSTANTS[0] is C_m in component environment (fF). * STATES[0] is q_K_o in component environment (fmol). * STATES[1] is q_K_i in component environment (fmol). * STATES[2] is q_Na_o in component environment (fmol). * STATES[3] is q_Na_i in component environment (fmol). * STATES[4] is q_x0_funny in component environment (fmol). * STATES[5] is q_x1_funny in component environment (fmol). * STATES[6] is q_mem in component environment (fC). * CONSTANTS[1] is R in component environment (J_per_K_per_mol). * CONSTANTS[2] is T in component environment (kelvin). * CONSTANTS[3] is F in component environment (C_per_mol). * ALGEBRAIC[13] is v_funny_K in component funny (fmol_per_sec). * ALGEBRAIC[14] is v_funny_Na in component funny (fmol_per_sec). * ALGEBRAIC[18] is I_mem_funny in component funny (fA). * CONSTANTS[4] is kappa_funny_Na in component funny_parameters (fmol_per_sec). * CONSTANTS[5] is kappa_funny_K in component funny_parameters (fmol_per_sec). * CONSTANTS[6] is kappa_R_xf in component funny_parameters (fmol_per_sec). * CONSTANTS[7] is K_Na_i in component funny_parameters (per_fmol). * CONSTANTS[8] is K_Na_o in component funny_parameters (per_fmol). * CONSTANTS[9] is K_K_i in component funny_parameters (per_fmol). * CONSTANTS[10] is K_K_o in component funny_parameters (per_fmol). * CONSTANTS[11] is K_x0_funny in component funny_parameters (per_fmol). * CONSTANTS[12] is K_x1_funny in component funny_parameters (per_fmol). * CONSTANTS[13] is zNa in component funny_parameters (dimensionless). * CONSTANTS[14] is zK in component funny_parameters (dimensionless). * CONSTANTS[15] is z_xff in component funny_parameters (dimensionless). * CONSTANTS[16] is z_xfr in component funny_parameters (dimensionless). * ALGEBRAIC[0] is mu_K_i in component funny (J_per_mol). * ALGEBRAIC[1] is mu_K_o in component funny (J_per_mol). * ALGEBRAIC[2] is mu_Na_i in component funny (J_per_mol). * ALGEBRAIC[3] is mu_Na_o in component funny (J_per_mol). * ALGEBRAIC[4] is V_mem in component funny (J_per_C). * ALGEBRAIC[6] is Am_Na in component funny (J_per_mol). * ALGEBRAIC[5] is Am_K in component funny (J_per_mol). * ALGEBRAIC[9] is Af_K in component funny (J_per_mol). * ALGEBRAIC[10] is Ar_K in component funny (J_per_mol). * ALGEBRAIC[11] is Af_Na in component funny (J_per_mol). * ALGEBRAIC[12] is Ar_Na in component funny (J_per_mol). * ALGEBRAIC[7] is mu_x0_funny in component funny (J_per_mol). * ALGEBRAIC[8] is mu_x1_funny in component funny (J_per_mol). * ALGEBRAIC[15] is Af_R_xf in component funny (J_per_mol). * ALGEBRAIC[16] is Ar_R_xf in component funny (J_per_mol). * ALGEBRAIC[17] is v_xf in component funny (fmol_per_sec). * RATES[1] is d/dt q_K_i in component environment (fmol). * RATES[0] is d/dt q_K_o in component environment (fmol). * RATES[3] is d/dt q_Na_i in component environment (fmol). * RATES[2] is d/dt q_Na_o in component environment (fmol). * RATES[6] is d/dt q_mem in component environment (fC). * RATES[4] is d/dt q_x0_funny in component environment (fmol). * RATES[5] is d/dt q_x1_funny in component environment (fmol). */ void initConsts(double* CONSTANTS, double* RATES, double *STATES) { CONSTANTS[0] = 153400; STATES[0] = 27.9828; STATES[1] = 5510; STATES[2] = 9.3276; STATES[3] = 0.00456; STATES[4] = 5.4799070E-06; STATES[5] = 5.4799070E-06; STATES[6] = -8.5e4; CONSTANTS[1] = 8.31; CONSTANTS[2] = 310; CONSTANTS[3] = 96500; CONSTANTS[4] = 45.0247; CONSTANTS[5] = 91.4974; CONSTANTS[6] = 0.188833; CONSTANTS[7] = 1.80864; CONSTANTS[8] = 13.2633; CONSTANTS[9] = 2.57828; CONSTANTS[10] = 18.9074; CONSTANTS[11] = 0.00306604; CONSTANTS[12] = 61.5887; CONSTANTS[13] = 1; CONSTANTS[14] = 1; CONSTANTS[15] = -1.8309039; CONSTANTS[16] = 0.787348905; } void computeRates(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[4] = STATES[6]/CONSTANTS[0]; ALGEBRAIC[5] = CONSTANTS[14]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[0] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[9]*STATES[1]); ALGEBRAIC[8] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[12]*STATES[5]); ALGEBRAIC[9] = ALGEBRAIC[8]+ALGEBRAIC[0]+ALGEBRAIC[5]; ALGEBRAIC[1] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[10]*STATES[0]); ALGEBRAIC[10] = ALGEBRAIC[8]+ALGEBRAIC[1]; ALGEBRAIC[13] = (ALGEBRAIC[5]==0.00000 ? 1.00000*CONSTANTS[5]*(exp(ALGEBRAIC[9]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[10]/( CONSTANTS[1]*CONSTANTS[2]))) : ((( 1.00000*CONSTANTS[5]*ALGEBRAIC[5])/( CONSTANTS[1]*CONSTANTS[2]))/(exp(ALGEBRAIC[5]/( CONSTANTS[1]*CONSTANTS[2])) - 1.00000))*(exp(ALGEBRAIC[9]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[10]/( CONSTANTS[1]*CONSTANTS[2])))); RATES[1] = - ALGEBRAIC[13]; RATES[0] = ALGEBRAIC[13]; ALGEBRAIC[6] = CONSTANTS[13]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[2] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[7]*STATES[3]); ALGEBRAIC[11] = ALGEBRAIC[8]+ALGEBRAIC[2]+ALGEBRAIC[6]; ALGEBRAIC[3] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[8]*STATES[2]); ALGEBRAIC[12] = ALGEBRAIC[8]+ALGEBRAIC[3]; ALGEBRAIC[14] = (ALGEBRAIC[6]==0.00000 ? 1.00000*CONSTANTS[4]*(exp(ALGEBRAIC[11]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[12]/( CONSTANTS[1]*CONSTANTS[2]))) : ((( 1.00000*CONSTANTS[4]*ALGEBRAIC[6])/( CONSTANTS[1]*CONSTANTS[2]))/(exp(ALGEBRAIC[6]/( CONSTANTS[1]*CONSTANTS[2])) - 1.00000))*(exp(ALGEBRAIC[11]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[12]/( CONSTANTS[1]*CONSTANTS[2])))); RATES[3] = - ALGEBRAIC[14]; RATES[2] = ALGEBRAIC[14]; ALGEBRAIC[7] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[11]*STATES[4]); ALGEBRAIC[15] = ALGEBRAIC[7]+ CONSTANTS[15]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[16] = ALGEBRAIC[8]+ CONSTANTS[16]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[17] = CONSTANTS[6]*(exp(ALGEBRAIC[15]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[16]/( CONSTANTS[1]*CONSTANTS[2]))); RATES[4] = - ALGEBRAIC[17]; RATES[5] = ALGEBRAIC[17]; ALGEBRAIC[18] = CONSTANTS[3]*(( - CONSTANTS[14]*ALGEBRAIC[13]+ CONSTANTS[13]*ALGEBRAIC[14]+ CONSTANTS[16]*ALGEBRAIC[17]) - CONSTANTS[15]*ALGEBRAIC[17]); RATES[6] = ALGEBRAIC[18]; } void computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC) { ALGEBRAIC[4] = STATES[6]/CONSTANTS[0]; ALGEBRAIC[5] = CONSTANTS[14]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[0] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[9]*STATES[1]); ALGEBRAIC[8] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[12]*STATES[5]); ALGEBRAIC[9] = ALGEBRAIC[8]+ALGEBRAIC[0]+ALGEBRAIC[5]; ALGEBRAIC[1] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[10]*STATES[0]); ALGEBRAIC[10] = ALGEBRAIC[8]+ALGEBRAIC[1]; ALGEBRAIC[13] = (ALGEBRAIC[5]==0.00000 ? 1.00000*CONSTANTS[5]*(exp(ALGEBRAIC[9]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[10]/( CONSTANTS[1]*CONSTANTS[2]))) : ((( 1.00000*CONSTANTS[5]*ALGEBRAIC[5])/( CONSTANTS[1]*CONSTANTS[2]))/(exp(ALGEBRAIC[5]/( CONSTANTS[1]*CONSTANTS[2])) - 1.00000))*(exp(ALGEBRAIC[9]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[10]/( CONSTANTS[1]*CONSTANTS[2])))); ALGEBRAIC[6] = CONSTANTS[13]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[2] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[7]*STATES[3]); ALGEBRAIC[11] = ALGEBRAIC[8]+ALGEBRAIC[2]+ALGEBRAIC[6]; ALGEBRAIC[3] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[8]*STATES[2]); ALGEBRAIC[12] = ALGEBRAIC[8]+ALGEBRAIC[3]; ALGEBRAIC[14] = (ALGEBRAIC[6]==0.00000 ? 1.00000*CONSTANTS[4]*(exp(ALGEBRAIC[11]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[12]/( CONSTANTS[1]*CONSTANTS[2]))) : ((( 1.00000*CONSTANTS[4]*ALGEBRAIC[6])/( CONSTANTS[1]*CONSTANTS[2]))/(exp(ALGEBRAIC[6]/( CONSTANTS[1]*CONSTANTS[2])) - 1.00000))*(exp(ALGEBRAIC[11]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[12]/( CONSTANTS[1]*CONSTANTS[2])))); ALGEBRAIC[7] = CONSTANTS[1]*CONSTANTS[2]*log( CONSTANTS[11]*STATES[4]); ALGEBRAIC[15] = ALGEBRAIC[7]+ CONSTANTS[15]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[16] = ALGEBRAIC[8]+ CONSTANTS[16]*CONSTANTS[3]*ALGEBRAIC[4]; ALGEBRAIC[17] = CONSTANTS[6]*(exp(ALGEBRAIC[15]/( CONSTANTS[1]*CONSTANTS[2])) - exp(ALGEBRAIC[16]/( CONSTANTS[1]*CONSTANTS[2]))); ALGEBRAIC[18] = CONSTANTS[3]*(( - CONSTANTS[14]*ALGEBRAIC[13]+ CONSTANTS[13]*ALGEBRAIC[14]+ CONSTANTS[16]*ALGEBRAIC[17]) - CONSTANTS[15]*ALGEBRAIC[17]); }