The University of Auckland, The Bioengineering Institute
Na Channel Mutation That Causes Both Brugada Syndrome and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism (INa1795insD Mutant Midmyocardial Cell)
This model is currently unable to be supported due to its dependence on the Luo Rudy 1994 model, which contains delay elements in its model of the CIRC, which can not yet be represented in CellML (as of CellML 1.1). Therefore this model is unconstrained and does not load or run in any simulator.
c.lloyd@auckland.ac.nz
The Bioengineering Institute
The University of Auckland
Colleen
Clancy
E
cardiac
Long QT Syndrome
na channel
electrophysiology
Brugada Syndrome
2002-03-12
Richard
Lawson
James
updated curation status,
removed publication link in documentation
The Clancy and Rudy's 2002 mathematical model of a Na channel mutation that causes both Brugada and long-QT syndrome phenotypes.
Ventricular Myocyte
Mammalia
2007-08-16T12:26:07+12:00
1208
Na Channel Mutation That Causes Both Brugada Syndrome and Long-QT Syndrome Phenotypes: A Simulation Study of Mechanism
105
1213
This is the CellML description of Clancy and Rudy's 2002 mathematical model of a Na channel mutation that causes both Brugada and long-QT syndrome phenotypes.
Lawson
James
Richard
Added value of 1.5e-2 to variable I_NaK (note, not i_NaK) in component "sodium_potassium_pump". This value was obtained from the LR94 dynamic model
Catherine
May
Lloyd
Circulation
11889015
keyword
2003-08-20T00:00:00+00:00
James Lawson
Rudy
Yoram
Catherine Lloyd
2009-06-05T15:14:35+12:00