# Size of variable arrays:
sizeAlgebraic = 3
sizeStates = 1
sizeConstants = 8
from math import *
from numpy import *

def createLegends():
    legend_states = [""] * sizeStates
    legend_rates = [""] * sizeStates
    legend_algebraic = [""] * sizeAlgebraic
    legend_voi = ""
    legend_constants = [""] * sizeConstants
    legend_voi = "time in component environment (minute)"
    legend_constants[0] = "PRA in component volume_receptors (mmHg)"
    legend_constants[7] = "AHZ in component effect_of_pressure_on_volume_receptors (dimensionless)"
    legend_constants[1] = "AH10 in component parameter_values (dimensionless)"
    legend_constants[2] = "AH9 in component parameter_values (per_mmHg)"
    legend_constants[6] = "AHZ1 in component effect_of_pressure_on_volume_receptors (dimensionless)"
    legend_states[0] = "AHY in component time_dependent_volume_receptor_adaptation (dimensionless)"
    legend_constants[3] = "AH11 in component parameter_values (minute)"
    legend_algebraic[0] = "AH7 in component total_volume_nervous_feedback (dimensionless)"
    legend_algebraic[1] = "ATRRFB in component volume_effect_on_arteries (dimensionless)"
    legend_constants[4] = "ATRFBM in component parameter_values (dimensionless)"
    legend_algebraic[2] = "ATRVFB in component volume_effect_on_unstressed_venous_volume (litre)"
    legend_constants[5] = "ATRVM in component parameter_values (litre)"
    legend_rates[0] = "d/dt AHY in component time_dependent_volume_receptor_adaptation (dimensionless)"
    return (legend_states, legend_algebraic, legend_voi, legend_constants)

def initConsts():
    constants = [0.0] * sizeConstants; states = [0.0] * sizeStates;
    constants[0] = 0.00852183
    constants[1] = 0.333
    constants[2] = 1
    states[0] = 0.301963
    constants[3] = 1000
    constants[4] = 0
    constants[5] = 0
    constants[6] = (power(fabs(constants[0]), constants[1]))*constants[2]
    constants[7] = custom_piecewise([less(constants[0] , 0.00000), -constants[6] , True, constants[6]])
    return (states, constants)

def computeRates(voi, states, constants):
    rates = [0.0] * sizeStates; algebraic = [0.0] * sizeAlgebraic
    rates[0] = (constants[7]-states[0])/constants[3]
    return(rates)

def computeAlgebraic(constants, states, voi):
    algebraic = array([[0.0] * len(voi)] * sizeAlgebraic)
    states = array(states)
    voi = array(voi)
    algebraic[0] = constants[7]-states[0]
    algebraic[1] = algebraic[0]*constants[4]+1.00000
    algebraic[2] = algebraic[0]*constants[5]
    return algebraic

def custom_piecewise(cases):
    """Compute result of a piecewise function"""
    return select(cases[0::2],cases[1::2])

def solve_model():
    """Solve model with ODE solver"""
    from scipy.integrate import ode
    # Initialise constants and state variables
    (init_states, constants) = initConsts()

    # Set timespan to solve over
    voi = linspace(0, 10, 500)

    # Construct ODE object to solve
    r = ode(computeRates)
    r.set_integrator('vode', method='bdf', atol=1e-06, rtol=1e-06, max_step=1)
    r.set_initial_value(init_states, voi[0])
    r.set_f_params(constants)

    # Solve model
    states = array([[0.0] * len(voi)] * sizeStates)
    states[:,0] = init_states
    for (i,t) in enumerate(voi[1:]):
        if r.successful():
            r.integrate(t)
            states[:,i+1] = r.y
        else:
            break

    # Compute algebraic variables
    algebraic = computeAlgebraic(constants, states, voi)
    return (voi, states, algebraic)

def plot_model(voi, states, algebraic):
    """Plot variables against variable of integration"""
    import pylab
    (legend_states, legend_algebraic, legend_voi, legend_constants) = createLegends()
    pylab.figure(1)
    pylab.plot(voi,vstack((states,algebraic)).T)
    pylab.xlabel(legend_voi)
    pylab.legend(legend_states + legend_algebraic, loc='best')
    pylab.show()

if __name__ == "__main__":
    (voi, states, algebraic) = solve_model()
    plot_model(voi, states, algebraic)