Model Mathematics

Component: environment

Component: rate_constants

k25=V25_Cdc25_T-Cdc25_P+V25__Cdc25_P kwee=Vwee_Wee1_P+Vwee__Wee1_T-Wee1_P k2=V2_UbE_T-UbE+V2__UbE

Component: concentration_variables

Component: cyclin

ddtimecyclin=k1AA-k2cyclin-k3cyclinCdc2

Component: cyclin_Cdc2

ddtimecyclin_Cdc2=kinhMPF_active-kwee+kcak+k2cyclin_Cdc2+k25Tyr15P_dimer+k3cyclinCdc2

Component: Tyr15P_dimer

ddtimeTyr15P_dimer=kweecyclin_Cdc2-k25+kcak+k2Tyr15P_dimer+kinhMPF_pre

Component: MPF_pre

ddtimeMPF_pre=kweeMPF_active-kinh+k25+k2MPF_pre+kcakTyr15P_dimer

Component: MPF_active

ddtimeMPF_active=kcakcyclin_Cdc2-kinh+kwee+k2MPF_active+k25MPF_pre

Component: Cdc2

Cdc2=Cdc2_T-cyclin_Cdc2+MPF_active+MPF_pre+Tyr15P_dimer

Component: cyclin_T

cyclin_T=cyclin+cyclin_Cdc2+MPF_active+MPF_pre+Tyr15P_dimer

Component: Cdc25_P

ddtimeCdc25_P=kaMPF_activeCdc25_T-Cdc25_PK_a+Cdc25_T-Cdc25_P-kbPPaseCdc25_PK_b+Cdc25_P

Component: Wee1_P

ddtimeWee1_P=keMPF_activeWee1_T-Wee1_PK_e+Wee1_T-Wee1_P-kfPPaseWee1_PK_f+Wee1_P

Component: IE_P

ddtimeIE_P=kgMPF_activeIE_T-IE_PK_g+IE_T-IE_P-khPPaseIE_PK_h+IE_P

Component: UbE

ddtimeUbE=kcIE_PUbE_T-UbEK_c+UbE_T-UbE-kd_antiIEUbEK_d+UbE