Generated Code

The following is c_ida code generated by the CellML API from this CellML file. (Back to language selection)

The raw code is available.

/*
   There are a total of 29 entries in the algebraic variable array.
   There are a total of 15 entries in each of the rate and state variable arrays.
   There are a total of 46 entries in the constant variable array.
 */
/*
 * VOI is time in component environment (minute).
 * CONSTANTS[0] is k1 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[1] is kn1 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[2] is k2 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[3] is kn2 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[4] is k2_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[5] is k3_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[6] is kn3_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[7] is k4 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[8] is k5 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[9] is k6 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[10] is k7 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[11] is kn7 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[12] is k8 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[13] is kn8 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[14] is k8_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[15] is k9 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[16] is kn9 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[17] is k9_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[18] is k10 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[19] is k11 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[20] is k12 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[21] is k13 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[22] is k14 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[23] is k14_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[24] is k15 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[25] is k16 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[26] is k17 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[27] is k18 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[28] is kn18 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[29] is k20 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[30] is k21 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[31] is k22 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[32] is k23 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[33] is kn23 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[34] is kPlk1 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[35] is kPlk1_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[36] is kctak1 in component rate_constants (first_order_rate_constant).
 * CONSTANTS[37] is kctak1_ in component rate_constants (first_order_rate_constant).
 * CONSTANTS[38] is kex in component rate_constants (first_order_rate_constant).
 * STATES[0] is Chk1P in component Chk1P (dimensionless).
 * ALGEBRAIC[3] is V_n1 in component V_n1 (first_order_rate_constant).
 * ALGEBRAIC[2] is V_1 in component V_1 (first_order_rate_constant).
 * STATES[1] is Rad3 in component Rad3 (dimensionless).
 * CONSTANTS[41] is V_4 in component V_4 (first_order_rate_constant).
 * ALGEBRAIC[9] is V_5 in component V_5 (first_order_rate_constant).
 * STATES[2] is p53 in component p53 (dimensionless).
 * CONSTANTS[42] is V_10 in component V_10 (first_order_rate_constant).
 * ALGEBRAIC[17] is V_11 in component V_11 (first_order_rate_constant).
 * STATES[3] is preMPF in component preMPF (dimensionless).
 * ALGEBRAIC[19] is V_14 in component V_14 (first_order_rate_constant).
 * ALGEBRAIC[16] is V_n9 in component V_n9 (first_order_rate_constant).
 * ALGEBRAIC[15] is V_9 in component V_9 (first_order_rate_constant).
 * STATES[4] is MPF in component MPF (dimensionless).
 * ALGEBRAIC[27] is V_n23 in component V_n23 (first_order_rate_constant).
 * ALGEBRAIC[26] is V_23 in component V_23 (first_order_rate_constant).
 * ALGEBRAIC[20] is V_15 in component V_15 (first_order_rate_constant).
 * STATES[5] is p21 in component p21 (dimensionless).
 * CONSTANTS[43] is V_21 in component V_21 (first_order_rate_constant).
 * ALGEBRAIC[24] is V_20 in component V_20 (first_order_rate_constant).
 * ALGEBRAIC[25] is V_22 in component V_22 (first_order_rate_constant).
 * STATES[6] is p21_MPF in component p21_MPF (dimensionless).
 * STATES[7] is iCdc25 in component iCdc25 (dimensionless).
 * ALGEBRAIC[12] is V_n7 in component V_n7 (first_order_rate_constant).
 * ALGEBRAIC[8] is V_n3_ in component V_n3_ (first_order_rate_constant).
 * ALGEBRAIC[11] is V_7 in component V_7 (first_order_rate_constant).
 * ALGEBRAIC[6] is V_2_ in component V_2_ (first_order_rate_constant).
 * CONSTANTS[39] is V_in in component V_in (first_order_rate_constant).
 * STATES[8] is iCdc25Ps216 in component iCdc25Ps216 (dimensionless).
 * ALGEBRAIC[23] is V_n18 in component V_n18 (first_order_rate_constant).
 * ALGEBRAIC[22] is V_18 in component V_18 (first_order_rate_constant).
 * ALGEBRAIC[7] is V_3_ in component V_3_ (first_order_rate_constant).
 * STATES[9] is iCdc25Ps216_protein1433 in component iCdc25Ps216_protein1433 (dimensionless).
 * ALGEBRAIC[28] is V_ex in component V_ex (first_order_rate_constant).
 * STATES[10] is aCdc25 in component aCdc25 (dimensionless).
 * ALGEBRAIC[5] is V_n2 in component V_n2 (first_order_rate_constant).
 * ALGEBRAIC[4] is V_2 in component V_2 (first_order_rate_constant).
 * STATES[11] is aCdc25Ps216 in component aCdc25Ps216 (dimensionless).
 * STATES[12] is protein1433 in component protein1433 (dimensionless).
 * ALGEBRAIC[10] is V_6 in component V_6 (first_order_rate_constant).
 * CONSTANTS[44] is V_13 in component V_13 (first_order_rate_constant).
 * ALGEBRAIC[18] is V_12 in component V_12 (first_order_rate_constant).
 * STATES[13] is Wee1 in component Wee1 (dimensionless).
 * CONSTANTS[45] is V_16 in component V_16 (first_order_rate_constant).
 * ALGEBRAIC[14] is V_n8 in component V_n8 (first_order_rate_constant).
 * ALGEBRAIC[13] is V_8 in component V_8 (first_order_rate_constant).
 * STATES[14] is Wee1P in component Wee1P (dimensionless).
 * ALGEBRAIC[21] is V_17 in component V_17 (first_order_rate_constant).
 * ALGEBRAIC[0] is aCdc25_T in component aCdc25_T (dimensionless).
 * ALGEBRAIC[1] is Chk1 in component V_1 (dimensionless).
 * CONSTANTS[40] is Chk1_T in component V_1 (dimensionless).
 * RATES[0] is d/dt Chk1P in component Chk1P (dimensionless).
 * RATES[1] is d/dt Rad3 in component Rad3 (dimensionless).
 * RATES[2] is d/dt p53 in component p53 (dimensionless).
 * RATES[3] is d/dt preMPF in component preMPF (dimensionless).
 * RATES[4] is d/dt MPF in component MPF (dimensionless).
 * RATES[5] is d/dt p21 in component p21 (dimensionless).
 * RATES[6] is d/dt p21_MPF in component p21_MPF (dimensionless).
 * RATES[7] is d/dt iCdc25 in component iCdc25 (dimensionless).
 * RATES[8] is d/dt iCdc25Ps216 in component iCdc25Ps216 (dimensionless).
 * RATES[9] is d/dt iCdc25Ps216_protein1433 in component iCdc25Ps216_protein1433 (dimensionless).
 * RATES[10] is d/dt aCdc25 in component aCdc25 (dimensionless).
 * RATES[11] is d/dt aCdc25Ps216 in component aCdc25Ps216 (dimensionless).
 * RATES[12] is d/dt protein1433 in component protein1433 (dimensionless).
 * RATES[13] is d/dt Wee1 in component Wee1 (dimensionless).
 * RATES[14] is d/dt Wee1P in component Wee1P (dimensionless).
 * There are a total of 0 condition variables.
 */
void
initConsts(double* CONSTANTS, double* RATES, double *STATES)
{
CONSTANTS[0] = 1;
CONSTANTS[1] = 10;
CONSTANTS[2] = 0.1;
CONSTANTS[3] = 0.01;
CONSTANTS[4] = 0.1;
CONSTANTS[5] = 100;
CONSTANTS[6] = 0;
CONSTANTS[7] = 0;
CONSTANTS[8] = 1;
CONSTANTS[9] = 0.01;
CONSTANTS[10] = 1;
CONSTANTS[11] = 0.01;
CONSTANTS[12] = 0.1;
CONSTANTS[13] = 0.01;
CONSTANTS[14] = 0;
CONSTANTS[15] = 1;
CONSTANTS[16] = 1;
CONSTANTS[17] = 0;
CONSTANTS[18] = 0;
CONSTANTS[19] = 1;
CONSTANTS[20] = 0.1;
CONSTANTS[21] = 1;
CONSTANTS[22] = 0.0005;
CONSTANTS[23] = 1;
CONSTANTS[24] = 0.01;
CONSTANTS[25] = 0.0002;
CONSTANTS[26] = 0.1;
CONSTANTS[27] = 1;
CONSTANTS[28] = 0.01;
CONSTANTS[29] = 0.1;
CONSTANTS[30] = 0.01;
CONSTANTS[31] = 0.1;
CONSTANTS[32] = 0.1;
CONSTANTS[33] = 1;
CONSTANTS[34] = 0;
CONSTANTS[35] = 0;
CONSTANTS[36] = 0;
CONSTANTS[37] = 0;
CONSTANTS[38] = 1;
STATES[0] = 0.000001;
STATES[1] = 0;
STATES[2] = 0;
STATES[3] = 0.000001;
STATES[4] = 0.00000001;
STATES[5] = 0;
STATES[6] = 0;
STATES[7] = 0.000001;
CONSTANTS[39] = 0.00001;
STATES[8] = 0.00002;
STATES[9] = 0.03;
STATES[10] = 0.000001;
STATES[11] = 0;
STATES[12] = 2;
STATES[13] = 0.001;
STATES[14] = 0;
CONSTANTS[40] = 1;
CONSTANTS[41] = CONSTANTS[7];
CONSTANTS[42] = CONSTANTS[18];
CONSTANTS[43] = CONSTANTS[30];
CONSTANTS[44] = CONSTANTS[21];
CONSTANTS[45] = CONSTANTS[25];
RATES[0] = 0.1001;
RATES[1] = 0.1001;
RATES[2] = 0.1001;
RATES[3] = 0.1001;
RATES[4] = 0.1001;
RATES[5] = 0.1001;
RATES[6] = 0.1001;
RATES[7] = 0.1001;
RATES[8] = 0.1001;
RATES[9] = 0.1001;
RATES[10] = 0.1001;
RATES[11] = 0.1001;
RATES[12] = 0.1001;
RATES[13] = 0.1001;
RATES[14] = 0.1001;
}
void
computeResiduals(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
                 double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
resid[0] = RATES[0] - ALGEBRAIC[2] - ALGEBRAIC[3];
resid[1] = RATES[1] - CONSTANTS[41] - ALGEBRAIC[9];
resid[2] = RATES[2] - CONSTANTS[42] - ALGEBRAIC[17];
resid[3] = RATES[3] - (ALGEBRAIC[19]+ALGEBRAIC[16]) - ALGEBRAIC[15];
resid[4] = RATES[4] - (ALGEBRAIC[15]+ALGEBRAIC[27]) - (ALGEBRAIC[16]+ALGEBRAIC[26]+ALGEBRAIC[20]);
resid[5] = RATES[5] - (ALGEBRAIC[24]+CONSTANTS[43]+ALGEBRAIC[27]) - (ALGEBRAIC[25]+ALGEBRAIC[26]);
resid[6] = RATES[6] - ALGEBRAIC[26] - ALGEBRAIC[27];
resid[7] = RATES[7] - (ALGEBRAIC[12]+ALGEBRAIC[8]+CONSTANTS[39]) - (ALGEBRAIC[11]+ALGEBRAIC[6]);
resid[8] = RATES[8] - (ALGEBRAIC[6]+ALGEBRAIC[23]) - (ALGEBRAIC[22]+ALGEBRAIC[7]);
resid[9] = RATES[9] - ALGEBRAIC[7] - (ALGEBRAIC[8]+ALGEBRAIC[28]);
resid[10] = RATES[10] - (ALGEBRAIC[11]+ALGEBRAIC[5]) - (ALGEBRAIC[12]+ALGEBRAIC[4]);
resid[11] = RATES[11] - (ALGEBRAIC[4]+ALGEBRAIC[22]) - (ALGEBRAIC[5]+ALGEBRAIC[23]);
resid[12] = RATES[12] - (ALGEBRAIC[10]+CONSTANTS[44]+ALGEBRAIC[8]) - (ALGEBRAIC[7]+ALGEBRAIC[18]);
resid[13] = RATES[13] - (CONSTANTS[45]+ALGEBRAIC[14]) - ALGEBRAIC[13];
resid[14] = RATES[14] - ALGEBRAIC[13] - (ALGEBRAIC[14]+ALGEBRAIC[21]);
}
void
computeVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[0] = STATES[10]+STATES[11];
}
void
computeEssentialVariables(double VOI, double* CONSTANTS, double* RATES, double* STATES, double* ALGEBRAIC)
{
ALGEBRAIC[1] = CONSTANTS[40] - STATES[0];
ALGEBRAIC[2] =  CONSTANTS[0]*ALGEBRAIC[1]*STATES[1];
ALGEBRAIC[3] =  CONSTANTS[1]*STATES[0];
ALGEBRAIC[4] =  CONSTANTS[2]*STATES[0]*STATES[10]+ CONSTANTS[36]*STATES[10];
ALGEBRAIC[5] =  CONSTANTS[3]*STATES[11];
ALGEBRAIC[6] =  CONSTANTS[4]*STATES[0]*STATES[7]+ CONSTANTS[37]*STATES[7];
ALGEBRAIC[7] =  CONSTANTS[5]*STATES[8]*STATES[12];
ALGEBRAIC[8] =  CONSTANTS[6]*STATES[9];
ALGEBRAIC[9] =  CONSTANTS[8]*STATES[1];
ALGEBRAIC[10] =  CONSTANTS[9]*STATES[2];
ALGEBRAIC[11] =  CONSTANTS[10]*STATES[4]*STATES[7]+ CONSTANTS[34]*STATES[7];
ALGEBRAIC[12] =  CONSTANTS[11]*STATES[10];
ALGEBRAIC[13] =  CONSTANTS[12]*STATES[4]*STATES[13]+ CONSTANTS[14]*STATES[13];
ALGEBRAIC[14] =  CONSTANTS[13]*STATES[14];
ALGEBRAIC[15] =  CONSTANTS[15]*(STATES[10]+STATES[11])*STATES[3]+ CONSTANTS[17]*STATES[3];
ALGEBRAIC[16] =  CONSTANTS[16]*STATES[4]*STATES[13];
ALGEBRAIC[17] =  CONSTANTS[19]*STATES[2];
ALGEBRAIC[18] =  CONSTANTS[20]*STATES[12];
ALGEBRAIC[19] =  (CONSTANTS[22]/(1.00000+ CONSTANTS[23]*STATES[2]))*1.00000;
ALGEBRAIC[20] =  CONSTANTS[24]*pow(STATES[4], 2.00000);
ALGEBRAIC[21] =  CONSTANTS[26]*STATES[14];
ALGEBRAIC[22] =  CONSTANTS[27]*STATES[4]*STATES[8]+ CONSTANTS[35]*STATES[8];
ALGEBRAIC[23] =  CONSTANTS[28]*STATES[11];
ALGEBRAIC[24] =  CONSTANTS[29]*STATES[2];
ALGEBRAIC[25] =  CONSTANTS[31]*STATES[5];
ALGEBRAIC[26] =  CONSTANTS[32]*STATES[4]*STATES[5];
ALGEBRAIC[27] =  CONSTANTS[33]*STATES[6];
ALGEBRAIC[28] =  CONSTANTS[38]*STATES[9];
}
void
getStateInformation(double* SI)
{
SI[0] = 1.0;
SI[1] = 1.0;
SI[2] = 1.0;
SI[3] = 1.0;
SI[4] = 1.0;
SI[5] = 1.0;
SI[6] = 1.0;
SI[7] = 1.0;
SI[8] = 1.0;
SI[9] = 1.0;
SI[10] = 1.0;
SI[11] = 1.0;
SI[12] = 1.0;
SI[13] = 1.0;
SI[14] = 1.0;
}
void
computeRoots(double VOI, double* CONSTANTS, double* RATES, double* OLDRATES, double* STATES,
             double* OLDSTATES, double* ALGEBRAIC, double* CONDVARS)
{
}